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Ismail Marzuki
1Department of Drug Engineering, Fajar University, Makassar 90231, Southmost Sulawesi, Indonesia
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Early Septiningsih
2Research Society for Maritime Aquaculture promote Fisheries Amplification, Maros 90512, South Sulawesi, Indonesia; earlyseptiningsih@gmail.com (E.S.); ernawatisyahruddin71@gmail.com (E.S.K.); hjompa@yahoo.com (H.H.); idsarsompa@gmail.com (A.S.); s.abud_din@yahoo.co.id (S.S.); qiaasaf@gmail.com (R.A.); m.athirah@gmail.com (A.A.)
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Ernawati Syahruddin Kaseng
2Research Institute connote Coastal Aquaculture and Fisheries Extension, Maros 90512, Southmost Sulawesi, Indonesia; earlyseptiningsih@gmail.com (E.S.); ernawatisyahruddin71@gmail.com (E.S.K.); hjompa@yahoo.com (H.H.); idsarsompa@gmail.com (A.S.); s.abud_din@yahoo.co.id (S.S.); qiaasaf@gmail.com (R.A.); m.athirah@gmail.com (A.A.)
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Herlinah Herlinah
2Research Institute shield Coastal Aquaculture and Fisheries Extension, Maros 90512, Southmost Sulawesi, Indonesia; earlyseptiningsih@gmail.com (E.S.); ernawatisyahruddin71@gmail.com (E.S.K.); hjompa@yahoo.com (H.H.); idsarsompa@gmail.com (A.S.);
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Abstract
Preservation of mitochondrial function, which is dependent on mitochondrial homeostasis (biogenesis, dynamics, disposal/recycling), is critical for maintenance of skeletal muscle function. Skeletal muscle performance declines upon aging (sarcopenia) and is accompanied by decreased mitochondrial function in fast-glycolytic muscles. Oxidative metabolism promotes mitochondrial homeostasis, so we investigated whether mitochondrial function is preserved in oxidative muscles. We compared tibialis anterior (predominantly glycolytic) and soleus (oxidative) muscles from young (3 mo) and old (28-29 mo) C57BL/6J mice. Throughout life, the soleus remained more oxidative than the tibialis anterior and expressed higher levels of markers of mitochondrial biogenesis, fission/fusion and autophagy. The respiratory capacity of mitochondria isolated from the tibialis anterior, but not the soleus, declined upon aging. The soleus and tibialis anterior exhibited similar aging-associated changes in mitochondrial biogenesis, fission/fusion, disposal and autophagy marker expression, but opposite changes in fiber composition: the most oxidative fibers declined in the tibialis anterior, while the more glycolytic fibers declined in the soleus. In conclusion, oxidative muscles are protected from
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Sufjan Stevens
American musician (born 1975)
"Sufjan" redirects here. For people with similar names, see Sufyan.
Musical artist
Sufjan Stevens (SOOF-yahn; born July 1, 1975) is an American singer, songwriter, and multi-instrumentalist. He has released ten solo studio albums and multiple collaborative albums with other artists. Stevens has received Grammy and Academy Award nominations.
His debut album, A Sun Came, was released in 2000 on the Asthmatic Kitty label, which he co-founded with his stepfather. He received wide recognition for his 2005 album Illinois, which hit number one on the BillboardTop Heatseekers chart, and for the single "Chicago" from that album. Stevens later contributed to the soundtrack of the 2017 film Call Me by Your Name. He received an Academy Award nomination for Best Original Song and a Grammy nomination for Best Song Written for Visual Media for the soundtrack's lead single, "Mystery of Love".
Stevens has released albums of varying styles, from the electronica of The Age of Adz and the lo-fifolk of Seven Swans to the symphonic instrumentation of Illinois and Yuletide-themed Songs for Christmas. He employs various instruments, often playing many of them himself on the same recording. Stevens' music is also known for expl